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[Wadden STEP 3, JAMA 2021] STEP 5 Trial (Nature Medicine 2022) Long-term data: patients maintained an average 15.2% weight loss over 2 years of continuous semaglutide use, with sustained metabolic improvements including reduced HbA1c, blood pressure, and waist circumference

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Often yes

Current research shows a possible association rather than confirmed causation, as patients taking semaglutide often have underlying risk factors including obesity and metabolic syndrome

Norepinephrine and dopamine regulate energy levels in the body, alertness, and sleep habits