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The intensity of the pain is similar to that of a sunburn

It is caused by repeated amplification of the CAG trinucleotide in the huntingtin (Htt) gene on the short arm of chromosome 4, which leads to a prolonged polyglutamine stretch at the N-terminus of the protein

If the cycle of necrosis and regeneration continues, there will be liver enlargement

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The highest uptake levels for both 3-PLG-dopa-A-GSH and 3-PLG-ibu-A-GSH were measured at the 24-h time-point: a significant, more than twofold elevation was obtained compared to the 1-h targeted groups (Fig