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These include excessive alcohol, which is metabolized through pathways that consume glutathione and generate oxidative stress

miRNA-23b, miR-221/222 levels positively correlate with the ESR, rheumatoid factor (RF), CRP, disease activity score (DAS), and anti-citrullinated protein antibodies (ACPA), which will become promising targets for RA detection (204)

Antioxidant activity and free radical scavenging properties of Spirulina

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IP6K3, located near the major histocompatibility complex, has previously been linked to other autoimmune diseases such as Graves disease and rheumatoid arthritis, indicating its potential role in the development of autoimmunity and HT [20]