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In HT, neurologic complications were found in 22% of patients and postural tachycardia syndrome (POTS) in 12%which may be in part be due to referral and ascertainment biases

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In particular, the treatment of adults carrying the diagnosis of obesity and moderate-to-severe obstructive sleep apnea with tirzepatide for 52 weeks has been associated with reduced levels of markers of systemic inflammation and improved sleep-related outcomes, including the apnea-hypopnea index, body weight, hypoxic burden, systolic blood pressure, and sleep-related patient-reported outcomes [38]