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GR is an essential enzyme that reduces oxidized glutathione (GSSG) back to its active, reduced form (GSH) as part of the AsA-GSH cycle, thereby maintaining cellular redox homeostasis 110

Copper and zinc interact significantly in their joint toxicity to Chlamydomonas reinhardtii : insights from physiological and transcriptomic investigations

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Both show dose-dependent GI side effects managed through escalation protocols