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191 Therefore, we discuss the current evidences discussing the relationship between SGLT-2 inhibition and SNS activity, as well as the possible role of central SGLT-2

Increasing the dosage and titration is standard, but you dont want to be 12 weeks in, a bit lighter and feeling confident again, about to go from 1 mg per week to 1.7 mg per week, when BOOM

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While semaglutide does not require dose adjustment based on renal function according to FDA labeling, patients with severe gastrointestinal adverse effects may experience dehydration that could impact renal function

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