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For readers who want more context around how we think about formulation, our piece on Why Supplement Studies Are So Confusing is a useful companion read

G.et al (2025)

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Subjective effects such as reduced energy improvement or slower skin tone changes may signal potency loss, but these arent definitive

Analysis of splenocytes demonstrated decreased CD4+IL-4+ and CD4+IL-17-secreting T cells when treated with high dose luteolin, which corresponded with the re-stimulation of splenocytes resulting in significant decreases in IL-4 expression [162]

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