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JAMA 2022;327(6):534e45

Other side effects, which are less common but might be more severe, could include: Vision changes Unusual mood changes Pounding heartbeat Talk to your doctor if you notice adverse effects, such as low blood sugar or kidney problems

GI side effects dominate both compounds

Side effect profiles are similar between brand and compounded: gastrointestinal effects (nausea, constipation, diarrhea) are the most common, especially during dose escalation

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Even after the gel packs are fully melted and warm, the insulated space maintains a lower temperature than the outside environment for additional hours