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Despite a lack of interaction between FOSL1 and ATF4, ATF4 might be involved in the regulation of phenotypic switch genes in a FOSL1-independent manner, e.g., by regulating MITF as described previously

Click counting means turning the dosage dial and counting the number of clicks to deliver a smaller dose than marked, like turning a 2.4 mg pen just 16 clicks to get 0.5 mg instead of selecting the correct pen

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