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Important safety considerations include: Not for use during pregnancy or breastfeeding Not for people under 18 years Not to be used alongside other GLP-1 receptor agonists Caution in people with a history of pancreatitis or gallbladder disease Risk of dehydration due to gastrointestinal side effects Potential hypoglycaemia risk when used with insulin or sulfonylureas Need for diabetic retinopathy monitoring in people with type 2 diabetes Suspected side effects should be reported via the MHRA Yellow Card Scheme

Semaglutide in Singapore - What You Need to Know about Glucagon-Like Peptide (GLP-1) 104398 Semaglutide injectable or pills used in the treatment of type 2 diabetes and obesity in Singapore

Data show that there were 1,176 cases of acute and chronic pancreatitis following tirzepatide use reported between January 2023 and June 2026, 18 of which had a fatal outcome

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