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Start at the inner corner below the eye, move outward along the under-eye, continue to the outer corner (crow's feet zone), then move to the upper orbital bone following the brow

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Full reconstitution guide Advanced calculator Dosing & Reconstitution Guide A single practical dilution with accurate once-daily dosing, step by step Standard / Gradual Approach (3 mL = ~1.67 mg/mL) Reconstitute: Add 3.0 mL bacteriostatic water to one 5 mg vial final concentration ~1.67 mg/mL (1,667 mcg/mL)

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Food and Drug Administration.

Han B, Zhu FX, Shi C, Wu HL, Gu XH