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Polymorphisms of renin-angiotensin system genes as a risk factor for high-altitude pulmonary oedema

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106 TNF has been involved in the process of endothelial cell activation, the induction of metalloproteinases and adhesion molecules, angiogenesis, and the regulation of fibroblast/keratinocyte/enterocyte chondrocyte/osteoclast activation, as well as other inflammatory cytokines