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On the other hand, unlike in BPC 157-rats (BPC 157 given alone), PT-values remained prolonged (warfarin-rats), here, after heparin, or warfarin, BPC 157+L-arginine-rats, BPC 157+L-NAME-rats, BPC 157+L-arginine+L-NAME-rats exhibited no reduced bleeding time and no effect on prolonged PT-, APTT-, TT- values (heparin-rats)

- COX-2 is involved in a number of "as-needed" or specialized functions including roles in inflammation, fever, pain, transduction of painful stimuli in the spinal cord, mitogenesis (particularly in the GI epithelium, and renal adaptation to stresses

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Regarding antioxidant capacity based on GSH, saline-CLP animals showed a decrease in serum GSH levels at 12 and 24 h (Figure 4D)