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It decreases with: Age Chronic stress Poor sleep Repeated dieting Gut irritation So when someone suddenly adds: 1020g of collagen per day Their digestive system simply isnt prepared

Research shows that most patients regain 50-75% of lost weight within one year of discontinuation, primarily because appetite hormones like ghrelin rebound to baseline levels

A disrupted microbiota during menopause can increase weight gain, anxiety, and gut inflammation

GIP is primarily produced by K cells in the proximal small intestine, while GLP-1 is secreted by L cells predominantly in the distal ileum and colon

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(1) While on these medications, patients often report feeling fuller sooner and for longer periods , which contributes to improved weight management